Help us Find a Cure for
Angelman Syndrome
Welcome to the Foundation for Angelman Syndrome Therapeutics UK.
We have one goal: to cure Angelman Syndrome.
What is Angelman Syndrome?
Drug Development Pipline
It’s our job to push forward all promising Angelman syndrome (AS) programs, and to ensure that the community has a birds-eye view of the entire landscape.
Meet Bella...
Has your loved one been newly diagnosed with Angelman Syndrome?
Need support or advice?
The Latest at FAST UK
Alton Towers IAD Weekend 2026 – Celebrating 13 Years!
The 2026 Alton Towers event for International Angelman Day marked an incredible 13 years of bringing families together for a weekend of fun, connection, and celebration!
FAST UK update note March 2026
Are you a caregiver for someone with Angelman syndrome? Your experiences are invaluable, and we want to hear from you.
Parent Blog: Carers Week 2026 – Please, give us a smile…by Sarah Washbrook
Please, give us a smile
I’m Mum to 6 year old Ivor, who lives with Angelman syndrome. This is a rare neurogenetic disorder affecting about 1 in 15,000 – about 500,000 worldwide.
People living with Angelman syndrome are significantly intellectually disabled, have balance and coordination issues, motor impairments and many have debilitating seizures.
Some will never walk. Most will never talk.
Life changing.
I’d like you to step into my life as a parent carer, just for one day.
Global Angelman Syndrome Registry
Your family’s experience can help build understanding of Angelman syndrome and support research towards treatments and a cure.
International Angelman Day @ Alton Towers
February 15th 2023, marks the 10 year anniversary of International Angelman Day, It is also the tenth year that an Angelman group, created by an Angelman mum, Linda Holmes, took place at their usual venue Alton Towers.
Global Angelman Syndrome Registry
Your family’s experience can help build understanding of Angelman syndrome and support research towards treatments and a cure.
Announcing the Winner of Our 2024 Community Member Award
We are thrilled to reveal the winner of our Community Member Award, an initiative recognizing individuals who’ve made a significant impact within the Angelman syndrome community in the UK.
Fundraising News
Peter’s fundraising journey: strength, courage and determination
Thomas’s Fulham raises over £6,500 for FAST UK
Ivor’s Splashathon raises £1,926 for FAST UK
Scientific Updates
Ultragenyx GTX-102 Aspire trial: community webinar recording
MavriX Bio announced that the FDA Rare Pediatric Disease Designation
Ionis shares update on CHAMPION Phase 3 clinical trial
Ultragenyx GTX-102 Aspire trial: community webinar recording
MavriX Bio announced that the FDA Rare Pediatric Disease Designation
Ionis shares update on CHAMPION Phase 3 clinical trial
FAST Global
This website is operated by FAST UK, an independent entity organised and existing under the laws of (England and Wales). While FAST UK uses the branding of the Foundation for Angelman Syndrome Therapeutics, FAST UK is a separate and distinct entity, operating under its own governance.
At FAST UK, we’re dedicated to keeping our community informed about advancements in Angelman syndrome treatments. We’ve provided a link to the global FAST site, where you can explore an up to date overview of the drug development pipeline. This resource highlights the progress of various programs, some of which are supported by FAST and others disclosed by external organisations.
Click below to gain insight into the promising developments bringing us closer to effective treatments and, ultimately, a cure.
Prof Art Beaudet
There are many disorders that will not be cured or treated in our lifetime, but Angelman Syndrome will not be one of them.